qsong-github/drugclaw/open-targets

Name: open-targets
Author: qsong-github

Claude Code and agent skill by qsong-github/drugclaw

Trust tier 3

community

Source check pending

Checking that the SKILL.md file is still in the repository.

Query the Open Targets Platform for drug-target-disease associations. Use whenever the user asks about drug targets, gene-disease associations, drug indications, clinical trial phases, or wants to look up any entity (Ensembl gene ID, ChEMBL drug ID, or free-text gene/drug name) in Open Targets. Also trigger when the user mentions Open Targets, ENSG IDs, CHEMBL IDs, or asks about target prioritization for diseases.

Install

npx vskill@latest install qsong-github/drugclaw/open-targets

SKILL.md

Open Targets Platform Query Skill

Query the Open Targets GraphQL API for drug, target, and disease association data. No API key required.

Entity Auto-Detection

Input Pattern	Detected As	Example
`ENSG00000...`	Target (Ensembl gene ID)	`ENSG00000146648` (EGFR)
`CHEMBL...`	Drug (ChEMBL ID)	`CHEMBL941` (Imatinib)
anything else	Free-text search	`BRCA1`, `aspirin`

API

Function	Input	Returns
`query(entity)`	single entity string	dict with type, name, associations
`query_batch(entities)`	list of entity strings	list[dict]
`summarize(result)`	query result dict	compact one-line text
`get_target_info(ensembl_id)`	Ensembl ID string	raw GraphQL response
`get_drug_info(chembl_id)`	ChEMBL ID string	raw GraphQL response
`search_entities(term)`	free-text string	raw GraphQL response

Return Format

Target result:

json

{"entity": "ENSG00000146648", "type": "target", "found": true,
 "symbol": "EGFR", "name": "epidermal growth factor receptor",
 "biotype": "protein_coding",
 "top_diseases": [{"disease": "lung carcinoma", "score": 0.78}]}

Drug result:

json

{"entity": "CHEMBL941", "type": "drug", "found": true,
 "name": "IMATINIB", "drug_type": "Small molecule",
 "max_phase": 4,
 "indications": [{"disease": "chronic myeloid leukemia", "phase": 4}]}

Search result:

json

{"entity": "BRCA1", "type": "search", "found": true,
 "hits": [{"id": "ENSG00000012048", "name": "BRCA1", "entity_type": "target"}]}

Usage

See if __name__ == "__main__" block in 12_Open_Targets_Platform.py for runnable examples covering: single target/drug/search query, batch query, and JSON output.

Source

Endpoint: https://api.platform.opentargets.org/api/v4/graphql
Docs: https://platform.opentargets.org/
Paper: https://doi.org/10.1093/nar/gkac1046

Security

Security scanPassed, 100 of 100Pattern checks on the skill's files.
Model reviewPassed

See the full security report

Quality evaluation

Task evaluationNot runNo evaluation yet. Run one in Skill Studio.

See evaluation results

Source

SKILL.md in the repositoryCheckingskills/dti/open_targets/SKILL.md

Popularity

Repository stars: 116
Repository forks: 3
7-day trend score: 24

Stars and forks are for the whole GitHub repository, not this skill alone. Not refreshed yet.

Works with

Any agent vskill installs to: 56 targets in all. These 39 have a page on this site.

Claude Code
Cursor
GitHub Copilot
Windsurf
Codex
Gemini CLI
Cline
Amp
Roo Code
Goose
Continue
Kilo Code
Junie
Trae
OpenHands
Qwen Code
AI Agent
Tabnine Chat
Sourcegraph Cody
Amazon Q
Firebase Genkit
Sweep
Devin
Phind
Mentat
Claude Desktop
Aider
GPT Pilot
Plandex
bolt.new
v0
Replit Agent
Anse
TypingMind
BetterChatGPT
LibreChat
Warp AI
Pieces
Fig AI

Embed badge

[![vskill VERIFIED](https://verified-skill.com/api/v1/skills/qsong-github/drugclaw/open-targets/badge)](https://verified-skill.com/skills/qsong-github/drugclaw/open-targets)

Something wrong with this skill or its page? Tell us.